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Article

KIF3a Promotes Proliferation and Invasion via Wnt Signaling in Advanced Prostate Cancer

11 Jan 2014

Abstract excerpt

UNLABELLED: Aberrant activation of the Wnt/β-catenin signaling pathway is a critical event in advanced prostate cancer, but the genetic alterations that activate the Wnt signaling pathway in many other cancers are rarely observed in prostate cancer. Other molecular mechanisms that regulate the Wnt signaling pathway in prostate cancer remain to be identified. Here, it is demonstrated that KIF3a, a subunit of...

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PMID: 24413182
DOI: 10.1158/1541-7786.mcr-13-0418

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