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Article

The Drosophila clock gene per affects intercellular junctional communication.

Nature - 1 Jan 2000

Bargiello T A, Saez L, Baylies M K, Gasic G, Young M W, Spray D C

Abstract excerpt

The per locus of Drosophila has been implicated in the control of behavioural rhythms. In fruitfly embryos and larvae per is expressed in salivary glands. Per mutations have striking effects on intercellular communication in salivary glands: gap junction channels are modulated so that their conductance varies inversely with the period of behavioural rhythms in the mutants. A similar effect on junctional...

Topics

Animals
Behavior, Animal
Biological Clocks
Cell Communication
Drosophila
Electrophysiology
Histocytochemistry
Intercellular Junctions
Mutation
Permeability
RNA
Salivary Glands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2441265
DOI: 10.1038/328686a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2441265-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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