Article
Expression of cytokeratin 20 indicates invasive histological phenotype in poorly differentiated colorectal adenocarcinoma.
Anticancer research - 1 Jan 2014
Imai Yasuo, Yamagishi Hidetsugu, Fukuda Kazunori, Okamura Takuya, Ono Yuko, Ban Shinichi, Inoue Tohru, Ueda Yoshihiko
Abstract excerpt
BACKGROUND/AIM: Cytokeratin (CK) 20 expression is an independent prognostic factor of poorly differentiated adenocarcinoma (PDA) of the colon and rectum. We aimed to investigate the mechanism of its involvement through a clinicopathological study. PATIENTS AND METHODS: We analyzed 156 surgically resected PDAs, which were sub-classified as solid type (Por1) showing expansive growth, or non-solid type (Por2)...
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