Article
Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
Atherosclerosis - 1 Jan 2014
McLeod Olga, Silveira Angela, Fredrikson Gunilla N, Gertow Karl, Baldassarre Damiano, Veglia Fabrizio, Sennblad Bengt, Strawbridge Rona J, Larsson Malin, Leander Karin, Gigante Bruna, Kauhanen Jussi, Rauramaa Rainer, Smit Andries J, Mannarino Elmo, Giral Philippe, Humphries Steve E, Tremoli Elena, de Faire Ulf, Ohrvik John, Nilsson Jan, Hamsten Anders
Abstract excerpt
OBJECTIVE: Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native and...
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