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Article

Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders.

Schizophrenia bulletin - 1 Nov 2014

Fisher Helen L, McGuffin Peter, Boydell Jane, Fearon Paul, Craig Thomas K, Dazzan Paola, Morgan Kevin, Doody Gillian A, Jones Peter B, Leff Julian, Murray Robin M, Morgan Craig

Abstract excerpt

BACKGROUND: Childhood abuse is considered one of the main environmental risk factors for the development of psychotic symptoms and disorders. However, this association could be due to genetic factors influencing exposure to such risky environments or increasing sensitivity to the detrimental impact of abuse. Therefore, using a large epidemiological case-control sample, we explored the interplay between a specific...

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Identifiers

PMID: 24399191
DOI: 10.1093/schbul/sbt201
PMCID: PMC4193698

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