Atypical Leber's hereditary optic neuropathy with molecular confirmation.

doi:10.1001/archneur.1993.00540050022009

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Article

Atypical Leber's hereditary optic neuropathy with molecular confirmation.

Archives of neurology - 1 May 1993

Weiner N C, Newman N J, Lessell S, Johns D R, Lott M T, Wallace D C

Abstract excerpt

OBJECTIVE: Leber's hereditary optic neuropathy (LHON) is typically a familial disease of primarily young, male adults. Analysis of mitochondrial DNA has identified point mutations associated with LHON and allowed us to identify cases of LHON not consistent with traditional descriptions of the dis...

Topics

Adult
Child
Female
Humans
Male
Middle Aged
Mitochondria
Mutation
Optic Atrophies, Hereditary
Vision Disorders
Visual Fields

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