Article

Retinal Sublayer Thickness Analysis of The Macula of Symptomatic and Asymptomatic Carriers of G11778A Mutations with Leber's Hereditary Optic Neuropathy

2022-03-18

Abstract excerpt

<h4>Background: </h4> Leber's hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial genetic disease, caused mainly by G11778A mutations. Analysis of retinal sublayer structure by spectral domain optical coherence tomography(SD-OCT) is of great significance for elucidating the pathogenesis of LHON. Purpose To analyze the thicknesses of the outer plexiform layer (OPL), outer nuclear layer (ONL)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8aea3b00-d150-5d82-b9f2-93dc63e228ed
DOI: 10.21203/rs.3.rs-1454379/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Retinal Sublayer Thickness Analysis of The Macula of Symptomatic and Asymptomatic Carriers of G11778A Mutations with Leber's Hereditary Optic NeuropathyDOI 10.21203/rs.3.rs-1454379/v1Read

THREE-DIMENSIONAL CHARACTERISTICS OF FOUR MACULAR INTRARETINAL LAYER THICKNESSES IN SYMPTOMATIC AND ASYMPTOMATIC CARRIERS OF G11778A MUTATION WITH LEBER'S HEREDITARY OPTIC NEUROPATHY.Semantic proximity Read

Variation in retinal nerve fiber layer thickness at different stages of Leber's hereditary optic neuropathy in patients with the ND4 G11778A mutation.Semantic proximity Read

[Measurement of retinal nerve fiber layer thickness in Leber hereditary optic neuropathy by optical coherence tomography].Semantic proximity Read

Significant Thinning of Peripapillary Retinal Nerve Fiber Layer in Leber’s Hereditary Optic Neuropathy: An Optical Coherence Tomography Angiography Analysis Running title: Running title: RNFL in LHON by OCTASemantic proximity Read

Optic Nerve Structural and Functional Changes in LHON-Affected and Asymptomatic Maternal Relatives: Association with H and HV Mitochondrial Haplogroups.Semantic proximity Read

Comparison of retinal nerve fibre layers between 11778 and 14484 mutations in Leber's hereditary optic neuropathy.Semantic proximity Read

Juvenile open-angle Glaucoma associated with Leber’s hereditary optic neuropathy: a case report and literature reviewSemantic proximity Read

Leber hereditary optic neuropathy-new insights and old challenges.Semantic proximity Read

[Clinical practice guidelines for Leber's hereditary optic neuropathy].Semantic proximity Read

Progress in diagnosis and treatment of Leber's hereditary optic neuropathy.Semantic proximity Read

PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation.Semantic proximity Read

[Leber hereditary optic neuropathy: update on genetics and pathomechanisms].Semantic proximity Read