Article
[Analysis of KRAS status in cancer tissue with submucosal or deeper invasion in patients with familial adenomatous polyposis].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Nov 2013
Tajima Yusuke, Kumamoto Kensuke, Takeuchi Ikuya, Baba Hiroyuki, Ishibashi Keiichiro, Tsuji Yoshitaka, Haga Norihiro, Inokuma Shigehisa, Iwama Takeo, Ishida Hideyuki
Abstract excerpt
The KRAS status in cancer tissue with submucosal or deeper invasion was investigated in patients with familial adenomatous polyposis (FAP). Fifteen cancerous lesions in 10 FAP patients were subjected to analysis for KRAS status. The clinical features of FAP were the dense type in 2 patients and the sparse type in 8 patients. Of the 15 cancerous lesions, 6 (40%) were identified as having wild-type KRAS and the...
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