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Article

A novel hypoxia-associated subset of FN1 high MITF low melanoma cells: identification, characterization, and prognostic value.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2014

Wouters Jasper, Stas Marguerite, Govaere Olivier, Barrette Kathleen, Dudek Aleksandra, Vankelecom Hugo, Haydu Lauren E, Thompson John F, Scolyer Richard A, van den Oord Joost J

Abstract excerpt

In many human cancers, the epithelial-to-mesenchymal transition has an important role in the induction of cancer stem-like cells, and hence, in the causation of intratumoral heterogeneity. This process, also referred to as mesenchymal mimicry, is, however, only poorly understood in melanoma and histological correlation is still lacking. In an immunohistochemical analysis of a large prospective series of 220...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24390218
DOI: 10.1038/modpathol.2013.228

Genes

MITF
NGFR
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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