Article
The mannose-sensitive hemagglutination pilus strain of Pseudomonas aeruginosa shift peritoneal milky spot macrophages towards an M1 phenotype to dampen peritoneal dissemination.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014
Miao Zhi-Feng, Zhao Ting-Ting, Miao Feng, Wang Zhen-Ning, Xu Ying-Ying, Mao Xiao-Yun, Gao Jian, Wu Jian-Hua, Liu Xing-Yu, You Yi, Xu Hao, Xu Hui-Mian
Abstract excerpt
Peritoneal dissemination (PD) of tumor cells is the most frequent pattern of gastric cancer recurrence and the leading cause of death. Peritoneal milky spots are deemed as the site of origin of gastric cancer PD wherein the main cellular components are macrophages. A vaccine derived from the mannose-sensitive hemagglutination pilus strain of Pseudomonas aeruginosa (PA-MSHA) has exhibit strong immune modulatory...
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