Article
Streptococcal infection as possible trigger for dense deposit disease (C3 glomerulopathy).
European journal of pediatrics - 1 Jun 2014
Prasto Julianne, Kaplan Bernard S, Russo Pierre, Chan Elaine, Smith Richard J, Meyers Kevin E C
Abstract excerpt
UNLABELLED: Dense deposit disease (DDD, formerly known as membranoproliferative glomerulonephritis (MPGN) type II) is a subtype of C3 glomerulopathy (C3G). Electron-dense deposits in the glomerular basement membrane characterize this glomerulonephritis. DDD typically presents with a nephritic syndrome that progresses to end-stage renal failure in 50 % of patients despite treatment. The pathogenic basis of DDD is...
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