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Article

Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.

World journal of gastroenterology - 21 Dec 2013

Gu De-Leung, Chen Yen-Hsieh, Shih Jou-Ho, Lin Chi-Hung, Jou Yuh-Shan, Chen Chian-Feng

Abstract excerpt

High-throughput short-read sequencing of exomes and whole cancer genomes in multiple human hepatocellular carcinoma (HCC) cohorts confirmed previously identified frequently mutated somatic genes, such as TP53, CTNNB1 and AXIN1, and identified several novel genes with moderate mutation frequencies, including ARID1A, ARID2, MLL, MLL2, MLL3, MLL4, IRF2, ATM, CDKN2A, FGF19, PIK3CA, RPS6KA3, JAK1, KEAP1, NFE2L2,...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24379610
DOI: 10.3748/wjg.v19.i47.8873
PMCID: PMC3870538

Genes

ARID2
ATM
AXIN1
CTNNB1
FGF19
JAK1
KEAP1
LEPR
RAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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