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Article

Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Feb 2014

Koon Henry B, Krown Susan E, Lee Jeannette Y, Honda Kord, Rapisuwon Suthee, Wang Zhenghe, Aboulafia David, Reid Erin G, Rudek Michelle A, Dezube Bruce J, Noy Ariela

Abstract excerpt

PURPOSE: Kaposi's sarcoma (KS) is a disease of multifocal vascular proliferation that requires infection with KS herpes virus (KSHV/HHV-8). Activation of the c-kit and platelet-derived growth factor (PDGF) receptors by autocrine/paracrine mechanisms follows endothelial cell KSHV infection. In a p...

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Identifiers

PMID: 24378417
DOI: 10.1200/JCO.2012.48.6365
PMCID: PMC3912327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24378417-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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