Article
Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population.
PloS one - 1 Jan 2013
Nakamura Akihiko, Niimura Hideshi, Kuwabara Kazuyo, Takezaki Toshiro, Morita Emi, Wakai Kenji, Hamajima Nobuyuki, Nishida Yuichiro, Turin Tanvir Chowdhury, Suzuki Sadao, Ohnaka Keizo, Uemura Hirokazu, Ozaki Etsuko, Hosono Satoyo, Mikami Haruo, Kubo Michiaki, Tanaka Hideo
Abstract excerpt
BACKGROUND/OBJECTIVE: Gene-gene interactions in the reverse cholesterol transport system for high-density lipoprotein-cholesterol (HDL-C) are poorly understood. The present study observed gene-gene combination effect and interactions between single nucleotide polymorphisms (SNPs) in ABCA1, APOA1, SR-B1, and CETP in serum HDL-C from a cross-sectional study in the Japanese population. METHODS: The study population...
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