Article
α-Hemolysin, not Panton-Valentine leukocidin, impacts rabbit mortality from severe sepsis with methicillin-resistant Staphylococcus aureus osteomyelitis.
The Journal of infectious diseases - 1 Jun 2014
Crémieux Anne-Claude, Saleh-Mghir Azzam, Danel Claire, Couzon Florence, Dumitrescu Oana, Lilin Thomas, Perronne Christian, Etienne Jérôme, Lina Gerard, Vandenesch François
Abstract excerpt
BACKGROUND: Severe sepsis, combining acute osteomyelitis and lung involvement, has been described increasingly in healthy children with the spread of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). METHODS: Outcomes (mortality, hematogenous spread, lung and bone involvements) of rabbit osteomyelitis caused by CA-MRSA LAC(WT) USA300 and its Panton-Valentine leukocidin (PVL)- and...
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