Histone Deacetylase 11 is an ε- <i>N</i> -Myristoyllysine Hydrolase

Abstract excerpt

<h4>SUMMARY</h4> Histone deacetylase (HDAC) enzymes are important regulators of diverse biological function, including gene expression, rendering them potential targets for intervention in a number of diseases, with a handful of compounds approved for treatment of certain hematologic cancers. Among the human zinc-dependent HDACs, the most recently discovered member, HDAC11, is the only member assigned to subclass...

Topics

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• Epigenetics and DNA Methylation
• Histone Deacetylase Inhibitors
• Histone Deacetylase Inhibitors Research
• Histone Deacetylases
• Ligands
• Peptidase Inhibition and Analysis
• Phenotype
• Protein Degradation and Inhibitors

Identifiers and source

Literature Corpus work

396e7cd7-f5d8-5dbb-bbee-18f84217d1f3

DOI

10.1101/211839