Article
High frequency of BRAF V600E mutation in Iranian population ameloblastomas.
Medicina oral, patologia oral y cirugia bucal - 1 Jul 2020
Derakhshan S, Aminishakib P, Karimi A, Saffar H, Abdollahi A, Mohammadpour H, Kharazi Fard M-J, Memarha A
Abstract excerpt
BACKGROUND: Ameloblastoma is a common locally invasive but slow-growing neoplasm of the jaws with an odontogenic origin. Association between BRAF V600E mutation and clinicopathologic features and behavior of ameloblastoma remains controversial. This study aimed to evaluate BRAF V600E gene mutation and expression of its related proteins with clinicopathologic parameters in conventional ameloblastoma. MATERIAL AND...
Topics
- Ameloblastoma
- Biomarkers, Tumor
- Humans
- Iran
- Mutation
- Neoplasm Recurrence, Local
- Proto-Oncogene Proteins B-raf