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Differentiation therapy for solid tumors

26 Dec 2013

Abstract excerpt

Differentiation therapy for tumors refers to treating malignant tumors via the induction of cell differentiation. The best characterized clinical application of differentiation therapy is the use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia (APL), which markedly improved the outcome of this disease. Unlike the situation with APL, the development of differentiation therapy for solid...

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PMID: 24373518
DOI: 10.1111/1751-2980.12122

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