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Article

Modulation of strain-specific differences in gene expression by cannabinoid type 2 receptor deficiency.

Calcified tissue international - 1 Apr 2014

Sophocleous Antonia, Sims Andrew H, Idris Aymen I, Ralston Stuart H

Abstract excerpt

Previous studies have shown that the skeletal consequences of cannabinoid receptor deficiency differ in different strains of mice. In order to explore the mechanisms responsible, we analysed global gene expression in bone from wild-type CD1 mice and littermates with targeted inactivation of the type 2 cannabinoid receptor (Cnr2 (-/-)) and compared the results with those obtained from a similar analysis of...

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PMID: 24370613
DOI: 10.1007/s00223-013-9823-6

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