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Article

Concurrent MCL1 and JUN amplification in pseudomyxoma peritonei: a comprehensive genetic profiling and survival analysis.

Journal of human genetics - 1 Mar 2014

Sio Terence T, Mansfield Aaron S, Grotz Travis E, Graham Rondell P, Molina Julian R, Que Florencia G, Miller Robert C

Abstract excerpt

Pseudomyxoma peritonei (PMP) is a rare abdominal malignancy. We hypothesized that next-generation exomic sequencing would identify recurrent mutations that may have prognostic or therapeutic implications. Ten patients were selected on the basis of availability of tissue and adequate follow-up. They were treated at our institution between September 2002 and August 2004. Using next-generation exomic sequencing, we...

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Source

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Identifiers

PMID: 24369359
DOI: 10.1038/jhg.2013.132
PMCID: PMC3973125

Genes

MCL1
JUN
GNAS
KRAS
MYC
NFKBIA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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