Variant GADL1 and response to lithium therapy in bipolar I disorder.

doi:10.1056/NEJMoa1212444

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Article

Variant GADL1 and response to lithium therapy in bipolar I disorder.

The New England journal of medicine - 9 Jan 2014

Chen Chien-Hsiun, Lee Chau-Shoun, Lee Ming-Ta Michael, Ouyang Wen-Chen, Chen Chiao-Chicy, Chong Mian-Yoon, Wu Jer-Yuarn, Tan Happy Kuy-Lok, Lee Yi-Ching, Chuo Liang-Jen, Chiu Nan-Ying, Tsang Hin-Yeung, Chang Ta-Jen, Lung For-Wey, Chiu Chen-Huan, Chang Cheng-Ho, Chen Ying-Sheue, Hou Yuh-Ming, Chen Cheng-Chung, Lai Te-Jen, Tung Chun-Liang, Chen Chung-Ying, Lane Hsien-Yuan, Su Tung-Ping, Feng Jung, Lin Jin-Jia, Chang Ching-Jui, Teng Po-Ren, Liu Chia-Yih, Chen Chih-Ken, Liu I-Chao, Chen Jiahn-Jyh, Lu Ti, Fan Chun-Chieh, Wu Ching-Kuan, Li Chang-Fang, Wang Kathy Hsiao-Tsz, Wu Lawrence Shih-Hsin, Peng Hsin-Ling, Chang Chun-Ping, Lu Liang-Suei, Chen Yuan-Tsong, Cheng Andrew Tai-Ann

Abstract excerpt

BACKGROUND: Lithium has been a first-line choice for maintenance treatment of bipolar disorders to prevent relapse of mania and depression, but many patients do not have a response to lithium treatment. METHODS: We selected subgroups from a sample of 1761 patients of Han Chinese descent with bipolar I disorder who were recruited by the Taiwan Bipolar Consortium. We assessed their response to lithium treatment...

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Identifiers

PMID: 24369049
DOI: 10.1056/NEJMoa1212444

Genes

GADL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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