Immunophenotypes associated with bipolar disorder and lithium treatment.

doi:10.1038/s41598-019-53745-7

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Article

Immunophenotypes associated with bipolar disorder and lithium treatment.

Scientific reports - 25 Nov 2019

Wu Tai-Na, Lee Chau-Shoun, Wu Bo-Jian, Sun Hsiao-Ju, Chang Chieh-Hsing, Chen Chun-Ying, Chen Chih-Ken, Wu Lawrence Shih-Hsin, Cheng Andrew Tai-Ann

Abstract excerpt

Immune dysfunction is implicated in the etiology of bipolar disorder. The single-nucleotide polymorphism rs17026688 in the gene encoding glutamate decarboxylase-like protein 1 (GADL1) has been found to be associated with lithium response in Han Chinese patients with bipolar I disorder (BDI). However, whether patients with GADL1 polymorphisms have different immunophenotypes is unknown. To address this issue,...

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PMID: 31767892
DOI: 10.1038/s41598-019-53745-7
PMCID: PMC6877517

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