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Article

Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

PLoS pathogens - 1 Jan 2013

Elks Philip M, Brizee Sabrina, van der Vaart Michiel, Walmsley Sarah R, van Eeden Fredericus J, Renshaw Stephen A, Meijer Annemarie H

Abstract excerpt

Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and d...

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Identifiers

PMID: 24367256
DOI: 10.1371/journal.ppat.1003789
PMCID: PMC3868520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24367256-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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