Article
miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor.
Cell - 19 Dec 2013
Cassidy Justin J, Jha Aashish R, Posadas Diana M, Giri Ritika, Venken Koen J T, Ji Jingran, Jiang Hongmei, Bellen Hugo J, White Kevin P, Carthew Richard W
Abstract excerpt
Gene expression has to withstand stochastic, environmental, and genomic perturbations. For example, in the latter case, 0.5%-1% of the human genome is typically variable between any two unrelated individuals. Such diversity might create problematic variability in the activity of gene regulatory n...
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