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Article

Common pattern of evolution of gene expression level and protein sequence in Drosophila.

Molecular biology and evolution - 1 Jul 2004

Nuzhdin Sergey V, Wayne Marta L, Harmon Kristy L, McIntyre Lauren M

Abstract excerpt

Sequence divergence scaled by variation within species has been used to infer the action of selection upon individual genes. Applying this approach to expression, we compared whole-genome whole-body RNA levels in 10 heterozygous Drosophila simulans genotypes and a pooled sample of 10 D. melanogaster lines using Affymetrix Genechip. For 972 genes expressed in D. melanogaster, the transcript level was below...

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PMID: 15034135
DOI: 10.1093/molbev/msh128

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