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Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer

21 Jan 2023

Abstract excerpt

BACKGROUND: Current diagnosis tools for prostate cancer (PCa) such as serum PSA detection and prostate biopsy cannot distinguish dormant tumors from invasive malignancies, either be used as prognosis marker for castration resistant prostate cancer (CRPC), the lethal stage of PCa patients. Exosomes have been widely investigated as promising biomarkers for various diseases. We aim to characterize the proteomic and...

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PMID: 36681849
DOI: 10.1186/s12967-022-03860-3

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