Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Momordica charantia (Bitter Melon) reduces obesity-associated macrophage and mast cell infiltration as well as inflammatory cytokine expression in adipose tissues.

PloS one - 1 Jan 2013

Bao Bin, Chen Yan-Guang, Zhang Lei, Na Xu Yan Lin, Wang Xin, Liu Jian, Qu Wei

Abstract excerpt

Obesity is a world-wide epidemic disease that correlates closely with type 2 diabetes and cardiovascular diseases. Obesity-induced chronic adipose tissue inflammation is now considered as a critical contributor to the above complications. Momordica charantia (bitter melon, BM) is a traditional Chinese food and well known for its function of reducing body weight gain and insulin resistance. However, it is unclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Adiposity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Inflammation Mediators

Share to Insulin Resistance

Share to Macrophages

Share to Mast Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 24358329
DOI: 10.1371/journal.pone.0084075
PMCID: PMC3866167

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Momordica charantia (Bitter Melon) reduces obesity-associated macrophage and mast cell infiltration as well as inflammatory cytokine expression in adipose tissues.PMID 24358329Read ↗

BMP4 facilitates beige fat biogenesis via regulating adipose tissue macrophagesSemantic proximity Read ↗

Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice.Semantic proximity Read ↗

Pantothenic acid alleviates fat deposition and inflammation by preventing JNK/P38 MAPK signaling pathwaySemantic proximity Read ↗

In vivo and in vitro studies to identify the hypoglycaemic constituents of Momordica charantia wild variant WB24Semantic proximity Read ↗

Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes.Semantic proximity Read ↗

High fat-induced inflammation in vascular endothelium can be improved by Abelmoschus esculentus and metformin via increasing the expressions of miR-146a and miR-155Semantic proximity Read ↗

Mast cells are not associated with systemic insulin resistance.Semantic proximity Read ↗

Adipose tissue recruitment of leukocytes.Semantic proximity Read ↗

Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes.Semantic proximity Read ↗

Impacts of the vegetable Urtica dioica on the intestinal T and B cell phenotype and macronutrient absorption in C57BL/6J mice with diet-induced obesity.Semantic proximity Read ↗

Effects of Methanolic Leaf Extract of <em>Clinacanthus nutans</em> on Fatty Acid Composition and Gene Expression in Male Obese MiceSemantic proximity Read ↗

4-Octyl itaconate attenuates glycemic deterioration by regulating macrophage polarization in mouse models of type 1 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.