Article
Mast cells are not associated with systemic insulin resistance.
European journal of clinical investigation - 1 Nov 2016
Einwallner Elisa, Kiefer Florian W, Di Caro Giuseppe, Orthofer Michael, Witzeneder Nadine, Hörmann Gregor, Itariu Bianca, Zeyda Maximilian, Penninger Josef M, Stulnig Thomas M, Esterbauer Harald, Todoric Jelena
Abstract excerpt
BACKGROUND: Infiltration of white adipose tissue (WAT) by inflammatory cells in obesity is considered to be a key event in the development of insulin resistance. Recently, mast cells (MCs) have been identified as new players in the pathogenesis of obesity. We aimed to investigate the relationship between MCs and various inflammatory markers in serum and WAT and to determine the role of MCs in the aetiology of...
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