Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome

14 Dec 2013

Abstract excerpt

BACKGROUND: Meconium displaces surfactant from the alveolar surface and inhibits its function. The development of active synthetic surfactants is complicated, especially to synthesize the hydrophobic surfactant proteins SP-B and SP-C. A synthetic surfactant, CHF5633 containing SP-B and SP-C analogs, has been designed to act similarly to the natural surfactant poractant alfa. OBJECTIVE: To test the resistance to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neonatal Respiratory Health Research
Share to Neuroscience of respiration and sleep
Share to Tracheal and airway disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24356240
DOI: 10.1159/000356065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration SyndromePMID 24356240Read ↗

Synthetic surfactants with SP ‐B and SP ‐C analogues to enable worldwide treatment of neonatal respiratory distress syndrome and other lung diseasesSemantic proximity Read ↗

A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndromeSemantic proximity Read ↗

Human Meconium Has High Phospholipase A2 Activity and Induces Cellular Injury and Apoptosis in Piglet LungsSemantic proximity Read ↗

Secretory phospholipase A2 pathway in various types of lung injury in neonates and infants: a multicentre translational study.Semantic proximity Read ↗

Synthetic surfactant food additives can cause intestinal barrier dysfunction.Semantic proximity Read ↗

A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activitiesSemantic proximity Read ↗

Early versus delayed selective surfactant treatment for neonatal respiratory distress syndromeSemantic proximity Read ↗

Pathophysiology and treatment of surfactant protein-B deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.