Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis C virus stimulates low-density lipoprotein receptor expression to facilitate viral propagation.

Journal of virology - 1 Mar 2014

Syed Gulam Hussain, Tang Huihui, Khan Mohsin, Hassanein Tarek, Liu Jingwen, Siddiqui Aleem

Abstract excerpt

UNLABELLED: Lipids play a crucial role in multiple aspects of hepatitis C virus (HCV) life cycle. HCV modulates host lipid metabolism to enrich the intracellular milieu with lipids to facilitate its proliferation. However, very little is known about the influence of HCV on lipid uptake from bloodstream. Low-density lipoprotein receptor (LDLR) is involved in uptake of cholesterol rich low-density lipoprotein (LDL)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Consensus Sequence
Share to Hepatitis C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins, LDL

Share to Proprotein Convertase 9

Share to Proprotein Convertases

Share to Receptors, LDL

Share to Serine Endopeptidases

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 24352472
DOI: 10.1128/JVI.02727-13
PMCID: PMC3958050

Genes

LDLR
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis C virus stimulates low-density lipoprotein receptor expression to facilitate viral propagation.PMID 24352472Read ↗

Cellular and molecular biology of HCV infection and hepatitisSemantic proximity Read ↗

Modulation of host lipid metabolism by hepatitis C virus: Role of new therapies.Semantic proximity Read ↗

Regulated Entry of Hepatitis C Virus into HepatocytesSemantic proximity Read ↗

Hepatitis C virus utilizes VLDLR as a novel entry pathwaySemantic proximity Read ↗

Hepatitis C Virus Life Cycle and Lipid MetabolismSemantic proximity Read ↗

Hepatitis C virus and proprotein convertase subtilisin/kexin type 9: a detrimental interaction to increase viral infectivity and disrupt lipid metabolism.Semantic proximity Read ↗

Exploitation of Lipid Components by Viral and Host Proteins for Hepatitis C Virus InfectionSemantic proximity Read ↗

Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity.Semantic proximity Read ↗

The cell biology of hepatitis C virus (HCV) lipid addiction: molecular mechanisms and its potential importance in the clinic.Semantic proximity Read ↗

Hepatitis C virus entry: beyond receptorsSemantic proximity Read ↗

Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expressionSemantic proximity Read ↗

The roles of different microRNAs in the regulation of cholesterol in viral hepatitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.