Article
Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers.
Journal of virology - 1 Mar 2014
Lai Jennifer I, Licht Anna F, Dugast Anne-Sophie, Suscovich Todd, Choi Ickwon, Bailey-Kellogg Chris, Alter Galit, Ackerman Margaret E
Abstract excerpt
UNLABELLED: Understanding the coordination between humoral and cellular immune responses may be the key to developing protective vaccines, and because genetic studies of long-term HIV-1 nonprogressors have associated specific HLA-B alleles with spontaneous control of viral replication, this subject group presents an opportunity to investigate relationships between arms of the adaptive immune system. Given...
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