Article
Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers.
AIDS (London, England) - 20 Feb 2013
French Martyn A, Center Rob J, Wilson Kim M, Fleyfel Ibrahim, Fernandez Sonia, Schorcht Anna, Stratov Ivan, Kramski Marit, Kent Stephen J, Kelleher Anthony D
Abstract excerpt
BACKGROUND: Natural control of HIV infection is associated with CD8 T-cell responses to Gag-encoded antigens of the HIV core and carriage of 'protective' human leukocyte antigen (HLA)-B alleles, but some HIV controllers do not possess these attributes. As slower HIV disease progression is associated with high levels of antibodies to HIV Gag proteins, we have examined antibodies to HIV proteins in controllers with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.