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Article

Early days of DNA repair: discovery of nucleotide excision repair and homology-dependent recombinational repair.

The Yale journal of biology and medicine - 13 Dec 2013

Rupp W Dean

Abstract excerpt

The discovery of nucleotide excision repair in 1964 showed that DNA could be repaired by a mechanism that removed the damaged section of a strand and replaced it accurately by using the remaining intact strand as the template. This result showed that DNA could be actively metabolized in a process that had no precedent. In 1968, experiments describing postreplication repair, a process dependent on homologous...

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PMID: 24348214
PMCID: PMC3848104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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