Article
A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders.
Investigative ophthalmology & visual science - 17 Dec 2013
Al-Ubaidi Muayyad R, Naash Muna I, Conley Shannon M
Abstract excerpt
Progressive inherited retinal degenerative disorders (PIRDDs) are the leading cause of blindness in developed countries, with AMD and RP constituting the majority of PIRDDs. Currently, over 8 million Americans have PIRDDs, and that number is estimated to drastically increase by the end of this decade. Although a mutant protein is expressed starting early during retinal development in patients with PIRDDs,...
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