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Article

Somatic mtDNA mutation spectra in the aging human putamen.

PLoS genetics - 1 Jan 2013

Williams Siôn L, Mash Deborah C, Züchner Stephan, Moraes Carlos T

Abstract excerpt

The accumulation of heteroplasmic mitochondrial DNA (mtDNA) deletions and single nucleotide variants (SNVs) is a well-accepted facet of the biology of aging, yet comprehensive mutation spectra have not been described. To address this, we have used next generation sequencing of mtDNA-enriched libr...

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Identifiers

PMID: 24339796
DOI: 10.1371/journal.pgen.1003990
PMCID: PMC3854840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24339796-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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