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Article

Association analysis of IL7R polymorphisms with inflammatory demyelinating diseases.

Molecular medicine reports - 1 Feb 2014

Kim Jason Yongha, Cheong Hyun Sub, Kim Ho Jin, Kim Lyoung Hyo, Namgoong Suhg, Shin Hyoung Doo

Abstract excerpt

Multiple sclerosis (MS) and neuromyelitis optica (NMO), which are referred to as inflammatory demyelinating diseases (IDDs), are autoimmune diseases affecting the central nervous system. Interleukin‑7 receptor (IL7R) encodes for a receptor protein that is important in the development of immune cells. Several studies have reported significant associations between IL7R polymorphisms and MS. The aim of the present...

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PMID: 24337176
DOI: 10.3892/mmr.2013.1863

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