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Dual role of the caspase enzymes in satellite cells from aged and young subjects

12 Dec 2013

Abstract excerpt

Satellite cell (SC) proliferation and differentiation have critical roles in skeletal muscle recovery after injury and adaptation in response to hypertrophic stimuli. Normal ageing hinders SC proliferation and differentiation, and is associated with increased expression of a number of pro-apoptotic factors in skeletal muscle. In light of previous studies that have demonstrated age-related altered expression of...

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PMID: 24336075
DOI: 10.1038/cddis.2013.472

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