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Article

Role of Apoptosis in Sarcopenia

1 Nov 2003

Abstract excerpt

Skeletal muscle atrophy and the loss of myofibers contribute to sarcopenia, a condition associated with normal aging. However, relatively little is known regarding the relevance of apoptosis to skeletal muscle homeostasis and the possible mechanisms involved, although evidence suggests that apoptosis may play a role during muscle aging. By age 80 it is estimated that humans generally lose 30%-40% of skeletal...

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Identifiers

PMID: 14630880
DOI: 10.1093/gerona/58.11.m999

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