Article
Variants in glucose- and circadian rhythm-related genes affect the response of energy expenditure to weight-loss diets: the POUNDS LOST Trial.
The American journal of clinical nutrition - 1 Feb 2014
Mirzaei Khadijeh, Xu Min, Qi Qibin, de Jonge Lilian, Bray George A, Sacks Frank, Qi Lu
Abstract excerpt
BACKGROUND: Circadian rhythm has been shown to be related to glucose metabolism and risk of diabetes, probably through effects on energy balance. Recent genome-wide association studies identified variants in circadian rhythm-related genes (CRY2 and MTNR1B) associated with glucose homeostasis. OBJECTIVE: We tested whether CRY2 and MTNR1B genotypes affected changes in measures of energy expenditure in response to a...
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