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Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations.

Gynecologic oncology - 1 Feb 2014

Conner James R, Meserve Emily, Pizer Ellen, Garber Judy, Roh Michael, Urban Nicole, Drescher Charles, Quade Bradley J, Muto Michael, Howitt Brooke E, Pearlman Mark D, Berkowitz Ross S, Horowitz Neil, Crum Christopher P, Feltmate Colleen

Abstract excerpt

OBJECTIVE: This study computed the risk of clinically silent adnexal neoplasia in women with germ-line BRCA1 or BRCA2 mutations (BRCA(m+)) and determined recurrence risk. METHODS: We analyzed risk reduction salpingo-oophorectomies (RRSOs) from 349 BRCA(m+) women processed by the SEE-FIM protocol and addressed recurrence rates for 29 neoplasms from three institutions. RESULTS: Nineteen neoplasms (5.4%) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24333842
DOI: 10.1016/j.ygyno.2013.12.009
PMCID: PMC3932113

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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