Article
Effect of Nicotinic acid/Laropiprant in the lipoprotein(a) concentration with regard to baseline lipoprotein(a) concentration and LPA genotype.
Metabolism: clinical and experimental - 1 Mar 2014
Cenarro Ana, Puzo José, Ferrando Juan, Mateo-Gallego Rocío, Bea Ana M, Calmarza Pilar, Jarauta Estíbaliz, Civeira Fernando
Abstract excerpt
BACKGROUND: Lipoprotein(a) [Lp(a)] is a lipoprotein in which apolipoproteinB-100 is linked to apolipoprotein(a) [apo(a)]. Significant variation in Lp(a) concentration is specific to LPA gene, which codes for apo(a). Nicotinic acid (NA) is used for treatment of dyslipidemias, and the lowering effect of NA on Lp(a) has been previously reported. OBJECTIVE: To evaluate the Lp(a) lowering effect of 1g/20mg and...
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