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Article

Apolipoprotein E polymorphism affects plasma levels of lipoprotein(a).

Atherosclerosis - 1 Oct 1991

de Knijff P, Kaptein A, Boomsma D, Princen H M, Frants R R, Havekes L M

Abstract excerpt

In a group of 303 healthy Caucasian adults of both sexes we studied the influence of the apolipoprotein E (apo E) polymorphism on plasma levels of Lipoprotein(a) (Lp(a). The APOE*2 allele was found to decrease the mean plasma Lp(a) level by 24.8%, whereas the APOE*4 allele increased the mean Lp(a) level by 25.7%. These effects were parallel to the effect of apo E polymorphism on plasma cholesterol and low density...

Topics

Alleles
Apolipoproteins E
Cholesterol
Cholesterol, LDL
Female
Humans
Lipoprotein(a)
Lipoproteins
Male
Middle Aged
Phenotype
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1836947
DOI: 10.1016/0021-9150(91)90111-f

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1836947-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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