Article
Apolipoprotein(a) gene polymorphisms (TTTTA)n and G/A-914 affect Lp(a) levels in ischemic heart disease patients from Serbia.
Wiener klinische Wochenschrift - 1 Jun 2005
Dincić Dragan, Zivković Maja, Stanković Aleksandra, Djurić Tamara, Vujanić Svetlana, Gligić Branko, Alavantić Dragan
Abstract excerpt
OBJECTIVES: Lipoprotein(a) (Lp(a)) concentration is determined primarily by the apolipoprotein(a) (apo(a)) gene. The pentanucleotide (TTTTA)n repeat and G/A-914 polymorphisms are in the 5' promoter region of the apo(a) gene. To elucidate whether these polymorphisms affect Lp(a) levels, a total of 211 Serbian adults were investigated. DESIGN: One hundred and eleven patients with ischemic heart disease and 100...
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