Article
Genetic factors may play a prominent role in the development of coronary heart disease dependent on important environmental factors.
Journal of internal medicine - 1 Jun 2014
Song C, Chang Z, Magnusson P K E, Ingelsson E, Pedersen N L
Abstract excerpt
OBJECTIVE: The aim of the study was to examine whether various lifestyle factors modify genetic influences on coronary heart disease (CHD). DESIGN: The effect of lifestyle factors [including smoking, sedentary lifestyle, alcohol intake and body mass index (BMI)] on risk of CHD was evaluated via Cox regression models in a twin study of gene-environment interaction. Using structure equation modelling, we estimated...
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