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Article

Host genome variations and risk of infections during induction treatment for childhood acute lymphoblastic leukaemia.

European journal of haematology - 1 Apr 2014

Lund Bendik, Wesolowska-Andersen Agata, Lausen Birgitte, Borst Louise, Rasmussen Kirsten Kørup, Müller Klaus, Klungland Helge, Gupta Ramneek, Schmiegelow Kjeld

Abstract excerpt

OBJECTIVES: To investigate association of host genomic variation and risk of infections during treatment for childhood acute lymphoblastic leukaemia (ALL). METHODS: We explored association of 34,000 single-nucleotide polymorphisms (SNPs) related primarily to pharmacogenomics and immune function to risk of infections among 69 ALL patients on induction therapy. RESULTS: Forty-eight (70%) patients experienced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24330153
DOI: 10.1111/ejh.12243

Genes

CBR1
CCL11
POLDIP3

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