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Article

Foetal and placental 11<i>β</i>‐<scp>HSD</scp>2: a hub for developmental programming

28 Oct 2013

Abstract excerpt

Foetal growth restriction (FGR), reflective of an adverse intrauterine environment, confers a significantly increased risk of perinatal mortality and morbidity. In addition, low birthweight associates with adult diseases including hypertension, metabolic dysfunction and behavioural disorders. A key mechanism underlying FGR is exposure of the foetus to glucocorticoids which, while critical for foetal development,...

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PMID: 24330050
DOI: 10.1111/apha.12187

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