Article
Evaluation of ultra-deep targeted sequencing for personalized breast cancer care.
Breast cancer research : BCR - 10 Dec 2013
Harismendy Olivier, Schwab Richard B, Alakus Hakan, Yost Shawn E, Matsui Hiroko, Hasteh Farnaz, Wallace Anne M, Park Hannah L, Madlensky Lisa, Parker Barbara, Carpenter Philip M, Jepsen Kristen, Anton-Culver Hoda, Frazer Kelly A
Abstract excerpt
INTRODUCTION: The increasing number of targeted therapies, together with a deeper understanding of cancer genetics and drug response, have prompted major healthcare centers to implement personalized treatment approaches relying on high-throughput tumor DNA sequencing. However, the optimal way to implement this transformative methodology is not yet clear. Current assays may miss important clinical information such...
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