Article
Genetic variant in 8q24 is associated with prognosis for gastric cancer in a Chinese population.
Journal of gastroenterology and hepatology - 1 Apr 2015
Ma Gaoxiang, Gu Dongying, Lv Chunye, Chu Haiyan, Xu Zhi, Tong Na, Wang Meilin, Tang Cuiju, Xu Yong, Zhang Zhengdong, Wang Baolin, Chen Jinfei
Abstract excerpt
BACKGROUND AND AIM: Single nucleotide polymorphisms (SNPs) located in long noncoding RNA CASC8 gene may influence the process of splicing and stability of messenger RNA conformation, resulting in the modification of its interacting partners. Genome-wide association studies have identified the SNP rs10505477 and SNP rs1562430 in CASC8 were associated with risk of the colorectal cancer (CRC) and breast cancer,...
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