Article
Development of a new laboratory test to evaluate antithrombin resistance in plasma.
Thrombosis research - 1 Feb 2014
Murata Moe, Takagi Akira, Suzuki Atsuo, Okuyama Eriko, Takagi Yuki, Ando Yumi, Kato Io, Nakamura Yuki, Murate Takashi, Matsushita Tadashi, Saito Hidehiko, Kojima Tetsuhito
Abstract excerpt
INTRODUCTION: We recently reported a variant prothrombin (p.Arg596Leu: prothrombin Yukuhashi) that confers antithrombin resistance to patients with hereditary thrombosis. To detect antithrombin resistance in plasma, we devised a laboratory test analyzing the kinetics of thrombin inactivation usin...
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