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Article

[Discovery and prospects of a novel thrombophilia: antithrombin resistance].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 2014

Takagi Yuki, Kojima Tetsuhito

Abstract excerpt

Pathogenesis of venous thromboembolism (VTE) known to be complex and multifactorial process involves the interaction of acquired factors and genetic predisposing conditions. Deficiency of natural anticoagulant factors such as antithrombin (AT), protein C and protein S increases the risk of a VTE. Recently, we have reported novel mechanism of hereditary thrombosis in a Japanese family, in which AT resistance was...

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PMID: 25163329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Discovery and prospects of a novel thrombophilia: antithrombin resistance].PMID 25163329Read ↗

[Antithrombin resistance: a new mechanism of inherited thrombophilia].Semantic proximity Read ↗

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Thrombosis from a prothrombin mutation conveying antithrombin resistance.Semantic proximity Read ↗

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Causative genetic mutations for antithrombin deficiency and their clinical background among Japanese patients.Semantic proximity Read ↗

[Congenital thrombophilia].Semantic proximity Read ↗

Antithrombin-resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation.Semantic proximity Read ↗

[Molecular mechanisms of recurrent venous thrombosis in two pedigrees with type I antithrombin deficiency].Semantic proximity Read ↗

Resistance to activated protein C caused by a factor V gene mutation.Semantic proximity Read ↗

[Phenotypic and genetic analysis of two pedigrees affected with hereditary antithrombin deficiency].Semantic proximity Read ↗

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